Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
Blog Article
1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected to bortezomib, a proteasome inhibitor Employed in the treatment of multiple myeloma. Its synthesis or review is essential for making certain the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets certain different types of cancer, such as Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their review is vital for optimizing the production approach 4-[2-(2-Amino-4 and guaranteeing large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to deal with breast most cancers, and these intermediates are involved in its generation.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist Utilized in the procedure of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is used in the synthesis of Afatinib-1 paclitaxel, a chemotherapy drug powerful in dealing with cancers which include ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and compact mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is associated with the synthesis of adamantane derivatives, that have a variety of programs, like antiviral Qualities.
Vildagliptin Intermediates: Used in the manufacture of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to regulate blood sugar levels.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of assorted gluconic acid derivatives, which are Employed in meals, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication applied to deal with style 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).